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Wu-Chuang A, Mateos-Hernandez L, Maitre A, Rego ROM, Šíma R, Porcelli S, Rakotobe S, Foucault-Simonin A, Moutailler S, Palinauskas V, Aželytė J, Sǐmo L, Obregon D, Cabezas-Cruz A. Microbiota perturbation by anti-microbiota vaccine reduces the colonization of Borrelia afzelii in Ixodes ricinus. Microbiome. Submitted!

Maitre A, Wu-Chuang A, Mateos-Hernández L, Piloto-Sardiñas E, Foucault-Simonin A, Cicculli V, Moutailler S, Paoli JP, Falchi A, Obregón D, Cabezas-Cruz A. Rickettsial pathogens drive microbiota assembly in Hyalomma marginatum and Rhipicephalus bursa ticks. Molecular Ecology. Accepted!

Svobodová K, Maitre A, Obregón D, Wu-Chuang A, Thaduri S, Locke B, de Miranda JR, Mateos-Hernández L, Krejčí AB, Cabezas-Cruz A. Gut microbiota assembly of Gotland varroa-surviving honey bees excludes major viral pathogens. Microbiological Research. Accepted!

Cabezas-Cruz A. Grand Challenges in Arachnid Microbiota and Diseases. Front. Arachn. Sci. Accepted!

Wu-Chuang A, Hartmann D, Maitre A, Mateos-Hernández L, Frantová H, Urbanová V, Obregon D, Cabezas-Cruz A, Perner J. Low microbial community complexity in adult stages and female midguts of Dermanyssus gallinae. Microbial Ecology. Accepted!

Fernández-Ruiz N, Pinecki-Socias S, Estrada-Peña A, Wu-Chuang A, Maitre A, Obregron D,  Cabezas-Cruz A, de Blas I, Nijhof AM. Decontamination protocols affect the internal microbiota of ticks. Parasites & Vectors. Accepted!

Hussain S, Hussain A, Aziz MU, Song B, Zeb J, Hasib FMY, Li J, Almendros A, Cabezas-Cruz A, George D, Sparagano O. First molecular confirmation of multiple zoonotic vector-borne diseases in pet dogs and cats of Hong Kong SAR. Ticks Tick Borne Dis. DOI: 10.1016/j.ttbdis.2023.102191.

Piloto-Sardiñas E, Cano-Argüelles AL, Maitre A, Wu-Chuang A, Mateos-Hernandez L, Corduneanu A, Obregon D, Oleaga A, Pérez-Sánchez R, Cabezas-Cruz A. Comparison of salivary gland and midgut microbiome in the soft ticks Ornithodoros erraticus and Ornithodoros moubata. Frontiers in Microbiology. DOI: 10.3389/fmicb.2023.1173609.

Mazuecos L, Alberdi P, Hernández-Jarguín A, Contreras M, Villar M, Cabezas-Cruz A, Simo L, González-García A, Díaz-Sánchez S, Neelakanta G, Bonnet SI, Fikrig E, de la Fuente J. 2023. Frankenbacteriosis targeting interactions between pathogen and symbiont to control infection in the tick vector. iScience. DOI: 10.1016/j.isci.2023.106697.


Corduneanu A, Wu-Chuang A, Maitre A, Obregon D, Sándor AD, Cabezas-Cruz A. 2023. Structural differences in the gut microbiome of bats using terrestrial vs. aquatic feeding resources. BMC Microbiology. 23: 93.

Rego ROM, Lopez JE, Cabezas-Cruz A. 2023. Editorial: Biological Drivers of Vector–Pathogen Interactions – Vol II. Front Cell Infect Microbiol. 13:1170834.

Aželytė J, Wu-Chuang A, Maître A, Žiegytė R, Mateos-Hernandez L, Obregon D, Palinauskas V, Cabezas-Cruz A. 2023. Avian malaria parasites modulate gut microbiome assembly in canaries. Microorganisms. 11(3), 563.


Díaz-Sánchez AA and Cabezas-Cruz A. 2023. Can Domestic Cats Act as Reservoirs of Cytauxzoon felis? Pathogens. 12(2), 266.

Cabezas-Cruz A and Banović P. 2023. Understanding Tick-Borne Encephalitis Virus Foci, a Tale of Two Mountains. Pathogens. 12(2), 265.


Ghafar A, Davies N, Tadepalli M, Cabezas-Cruz A, Moutailler S, Foucault-Simonin A, Gauci CG, Stenos J, Hufschmid J, Jabbar A. 2023. Unravelling the diversity of microorganisms in ticks from Australian wildlife. Pathogens. 12(2), 153.

Zeb J, Song B, Senbill H, Aziz MU, Hussain S, Khan MA, Qadri I, Cabezas-Cruz A, de la Fuente J, Sparagano OA. 2023. Ticks infesting dogs in Khyber Pakhtunkhwa, Pakistan: First epidemiological and molecular report. Pathogens. 12(1), 98.



Banović P, Díaz-Sánchez AA, Foucault-Simonin A, Mateos-Hernandez L, Wu-Chuang A, Galon C, Simin V, Mijatović D, Bogdan I, Corona-González B, Coronado Báez L, Kulisz J, Woźniak A, Zając Z, Obregón D, Moutailler S, Cabezas-Cruz A. 2022. Emerging tick-borne spotted fever group rickettsioses in the Balkans. MEEGID. 105400.

Hodžić A, Dheilly NM, Cabezas-Cruz A, Berry D. 2022. Holobiont of metazoan parasites: Multi-dimensional host-parasite-microbiota interactions. Trends Parasitol. S1471-4922(22)00285-9.

Cabezas-Cruz A, Fogaça AC. 2022. Lock and Key: Why Rickettsia endosymbionts do not harm vertebrate hosts? Pathogens. 11(12), 1494.

Cabezas-Cruz A, Maitre A. 2022. Is Plant microbiota a driver of resistance to the vector-borne pathogen Xylella fastidiosa? Pathogens. 11(12), 1492.

Dragonjić LP, Vrbić M, Tasić A, Simin V, Bogdan I, Mijatović D, Cabezas-Cruz A, Banović P. 2022. Fatal Case of Imported Tick-Borne Encephalitis in South Serbia. Trop. Med. Infect. Dis. 7(12), 434.

Paulino PG, Peckle M, Mendonça LP, Massard CL, Antunes S, Couto J, Domingos A, Guedes Junior DS, Cabezas-Cruz A, Santos HA. 2022. Differential expression of immune genes in the Rhipicephalus microplus gut in response to Theileria equi infection. Pathogens. 11(12), 1478.

Banović P, Piloto-Sardiñas E, Mijatović D, Foucault-Simonin A, Simin V, Bogdan I, Obregón D, Mateos-Hernández L, Moutailler S, Cabezas-Cruz A. 2022. Differential detection of tick-borne pathogens in human platelets and whole blood using microfluidic PCR. Acta Tropica.  238: 106756.

Zając Z, Kulisz J, Kunc-Kozioł R, Woźniak A, Filipiuk M, Rudolf R, Bartosik K, Cabezas-Cruz A. 2022. Tick infestation in migratory birds of the Vistula River valley, Poland. IJERPH. 19(21), 13781.


Jakimovski D, Mateska S, Simin V, Bogdan I, Mijatović D, Estrada-Peña A, Mateos-Hernández L, Foucault-Simonin A, Moutailler S, Cabezas Cruz A, Banović P. 2022. Mediterranean spotted fever-like illness caused by Rickettsia sibirica mongolitimonae, North Macedonia, June 2022. Eurosurveillance. 27(42):pii=2200735.


Hussain S, Hussain A, Aziz MU, Song B, Zeb J, Hasib FMY, Li J, Rehman A, George D, Cabezas-Cruz A, and Sparagano O. 2022. First serological evidence of Q fever in large ruminants and its associated risk factors in Punjab, Pakistan. Scientific Reports. 12(1):17278.

Obregon D, Wu-Chuang A, Cabezas-Cruz A. 2022. Editorial: Insights into the relationships between host and vector microbiota, host health and response to disease. Front Vet Sci. 9:1002247. doi: 10.3389/fvets.2022.1002247.

Wu-Chuang A, Bates KA, Obregon D, Estrada-Peña A, King KC, Cabezas-Cruz A. 2022. Rapid evolution of a novel protective symbiont into keystone taxon in Caenorhabditis elegans microbiota. Scientific Reports. 12:14045. doi: 10.1038/s41598-022-18269-7.

Navarrete MG, Hodžić A, Corona-González B, Cordeiro MD, da Silva CB, Báez LC, Obregón D, Aguiar DM, Campos ANS, Taques IIGG, Wu-Chuang A, López ER, Piloto-Sardiñas E, Abuin-Denis L, Fonseca AH, Cabezas-Cruz A. 2022. Novel Ehrlichia canis genogroup in dogs with canine ehrlichiosis in Cuba. Parasit Vectors. 15:295.

Maitre A, Wu-Chuan A, Mateos-Hernández L, Foucault-Simonin A, Moutailler S, Paoli J-C, Falchi A, A. Díaz-Sánchez A, Banović P, Obregón D, Cabezas-Cruz A. 2022. Rickettsia helvetica infection is associated with microbiome modulation in Ixodes ricinus collected from humans in Serbia. Scientific Reports. 12:11464.


Juste R, Ferreras-Colino E, de la Fuente J, Domínguez M, Risalde MA, Domínguez L, Cabezas-Cruz A, Gortázar C. 2022. Heat inactivated mycobacteria, alpha-gal and zebra fish: insights gained from experiences with two promising trained immunity inductors and a validated animal model. Immunology. doi: 10.1111/imm.13529.

Thorel M, Mateos-Hernandez L, Mulot B, Azzouni MN, Hodžić A, Gaillot H, Ruel Y, Desoubeaux G, Delaye J-B, Obregon D, Wu-Chuang A, de la Fuente J, Bermúdez-Humarán LG, Risco-Castillo V, Leclerc A, Cabezas-Cruz A. 2022. Assessment of the safety and efficacy of an oral probiotic-based vaccine against Aspergillus infection in captive-bred Humboldt penguins. Front. Immunol. 13:897223. doi: 10.3389/fimmu.2022.897223.

Aželytė J, Wu-Chuang A, Žiegytė R, Platonova E, Mateos-Hernandez L, Maye J, Obregon D, Palinauskas V, Cabezas-Cruz A. 2022. Anti-microbiota vaccine reduces avian malaria infection within mosquito vectors. Front. Immunol. 13:841835.

Palinauskas V, Mateos-Hernandez L, Wu-Chuang A, de la Fuente J, Aželytė J, Obregón D, Cabezas-Cruz A. 2022. Exploring the ecological implications of microbiota diversity in birds: natural barriers against avian malaria. Front. Immunol. 13:807682.

Maître A; Wu-Chuang A; Aželytė J; Palinauskas V; Mateos-Hernández L; Obregon D; Hodžić A; Valiente Moro C; Estrada-Peña A; Paoli J-C; Falchi A; Cabezas-Cruz A. 2022. Vector microbiota manipulation by host antibodies: the forgotten strategy to develop transmission-blocking vaccines. Parasit Vectors. 15(1):4.

Banović P, Díaz-Sánchez AA, Simin V, Foucault-Simonin A, Galon C, Wu-Chuang A, Mijatović D, Obregón D, Moutailler S  Cabezas-Cruz A. 2022. Clinical Aspects and Detection of Emerging Rickettsial Pathogens: A “One Health” Approach Study in Serbia, 2020. Front. Microbiol. 12:797399.

Banović P, Díaz-Sánchez AA, Đurić S, Sević S, Turkulov V, Lendak D, Mikić SS, Simin V, Mijatović D, Bogdan I, Potkonjak A, Savić S, Obregón D, Cabezas- Cruz A. 2022. Unexpected TBEV seropositivity in Serbian patients who recovered from viral meningitis and encephalitis. Pathogens. 11(3), 371.

Bamgbose T, Alberdi P, Abdullahi IO, Inabo HI, Bello M, Sinha S, Anvikar AR, Mateos-Hernandez L, Torres-Maravilla E, Bermúdez-Humarán LG, Cabezas-Cruz A, de la Fuente J. 2022. Functional characterization of α-Gal producing lactic acid bacteria with potential probiotic properties. Scientific Reports. 12, 7484.

Hussain S, Perveen N, Hussain A, Song B, Aziz MU, Zeb J, Li J, George D, Cabezas-Cruz A, Sparagano O. 2022. The symbiotic continuum within ticks: opportunities for disease control. Front Microbiol. 13:854803.

Leannec-Rialland V, Atanasova V, Chereau S, Tonk-Rügen M, Cabezas-Cruz A, Richard-Forget F. 2022. Use of defensins to develop eco-friendly alternatives to synthetic fungicides to control phytopathogenic fungi and their mycotoxins. J Fungi. 8(3), 229.

Moraga-Fernandez A, Antonio Ortiz J, Jabbar A, Ghafar A, Cabezas-Cruz A, de la Fuente G, de la Fuente J, Fernández de  Mera IG. 2022. Fatal cases of bovine anaplasmosis in a herd infected with different Anaplasma marginale genotypes in Southern Spain. Ticks Tick Borne Dis.13(1):101864.

Fuentes D, Cabezas-Cruz A, Mesa C, Carmenate T, Martínez D, Valdés-Zayas A, Montero E, and Pérez R. 2022. Murine mammary carcinoma induces chronic systemic inflammation and immunosuppression in BALB/c mice. J. Breast Cancer. 25:e18.



Wu-Chuang A, Obregon D, Estrada-Peña A, Cabezas-Cruz A. 2021. Thermostable keystone bacteria maintain the functional diversity of the Ixodes scapularis microbiome under heat stress. Microbial Ecology. doi: 10.1007/s00248-021-01929-y.

Villar M, Pacheco I, Mateos-Hernández L, Cabezas-Cruz A, Tabor AE, Rodríguez-Valle M, Mulenga A, Kocan K, Blouin EF, de la Fuente J. 2021. Characterization of tick salivary gland and saliva alphagalactome reveals candidate alpha-gal syndrome disease biomarkers. Expert Reviews in Proteomics. doi: 10.1080/14789450.2021.2018305.

Grujić J, Bujandrić N, Budakov-Obradović Z, Dolinaj V, Bogdan D, Savić N, Cabezas-Cruz A, Mijatović D, Simin V, Anđelić N, Banović P. 2021. Demographic and Clinical Factors Associated with Reactivity of Anti-SARS-CoV-2 Antibodies in Serbian Convalescent Plasma Donors. International Journal of Environmental Research and Public Health. 19(1), 42.

Román-Carrasco P, Hemmer W, Cabezas-Cruz A, Hodžic A, de la Fuente J, Swoboda I. 2021. The α-Gal Syndrome and potential mechanisms. Frontiers in Allergy. doi: 10.3389/falgy.2021.783279.

Charles RA, Bermúdez S, Banović P, Obregón D, Díaz-Sánchez AA, Corona-González B, Etter E, González IR, Ghafar A, Jabbar A, Moutailler S, Cabezas-Cruz A. 2021. Ticks and tick-borne diseases in Central America and the Caribbean: A One Health Perspective. Pathogens. 10(10), 1273.

Gomez-Chamorro A, Hodžić A, King KC, Cabezas-Cruz A. 2021. Ecological and evolutionary perspectives on tick-borne pathogen co-infections. Current Research in Parasitology & Vector-Borne Diseases. doi: 10.1016/j.crpvbd.2021.100049.

Mateos-Hernández L, Obregon D, Wu-Chuang A, Maye J, Bornères J, Versillé N, de la Fuente J, Díaz-Sánchez S, Bermúdez-Humarán LG, Torres-Maravilla E, Estrada-Peña A, Hodžić A, Šimo L, Cabezas-Cruz A. 2021. Anti-microbiota vaccines modulate the tick microbiome in a taxon-specific manner. Front Immunol. 12:704621. doi: 10.3389/fimmu.2021.704621.

Wu-Chuang A, Obregon D, Mateos-Hernández L, Cabezas-Cruz A. 2021. Anti-tick microbiota vaccines: how can this actually work? Biologia. DOI: 10.1007/s11756-021-00818-6

Banović P, Díaz-Sánchez AA, Galond C, Foucault-Simonind A, Simine V, Mijatovića D, Papić L, Wu-Chuang A, Obregón D, Moutaillerd S, Cabezas-Cruz A. 2021. A One Health approach to study the circulation of tick-borne pathogens: a preliminary study. One Health. DOI: 10.1016/j.onehlt.2021.100270

Wu-Chuang A, Hodžić A, Mateos-Hernández L, Estrada-Peña A, Obregon D, Cabezas-Cruz A. 2021. Current debates and advances in tick microbiome research. Current Research in Parasitology & Vector-Borne Diseases. DOI: 10.1016/j.crpvbd.2021.100036

Cabezas-Cruz A, Hodžić A, Mateos-Hernández L, Contreras M, de la Fuente J. 2021. Tick-human interactions: from allergic klendusity to the α-Gal syndrome. Biochemical Journal. 478(9):1783-1794.

Banović P, Díaz-Sanchez AA, Mijatović D, Vujin D, Zsolt H, Vranješ N, Budakov Z, Bujandrić N, Grujić J, Ghafar A, Jabbar A, Simin V, Obregón D, Cabezas-Cruz A. 2021. Shared odds of Borrelia and rabies virus exposure in Serbia. Pathogens. 10(4), 399.


Leannec-Rialland V*, Cabezas-Cruz A*,-1, Atanasova V, Chereau S, Ponts N, Tonk M, Vilcinskas A, Ferrer N, Valdés JJ, Richard-Forget F-1. 2021. Tick defensin γ-core reduces Fusarium graminearum growth and abrogates mycotoxins production with high efficiency. Scientific Reports. 11(1):7962. *Joint first authors and '1' joint corresponding authors.

Banović P, Obregón D, Mijatović D, Simin V, Stankov S, Budakov Z, Bujandrić N, Grujić J, Sević S, Turkulov V,  Díaz-Sánchez AA, Cabezas-Cruz A. 2021. Tick-borne encephalitis virus seropositivity among tick infested individuals in Serbia. Pathogens. 10(3), 301.

Banović P, Díaz-Sánchez AA, Galon C, Simin V, Mijatović D, Obregón D, Moutailler S, Cabezas-Cruz A. 2021. Humans infested with Ixodes ricinus are exposed to a diverse array of tick-borne pathogens in Serbia. Ticks Tick Borne Dis. 12(2):101609.

de la Fuente J, Gortázar C, Cabezas-Cruz A. 2021. Immunity to glycan α-Gal and possibilities for the control of COVID-19. Immunotherapy. 13(3):185-188.

Tonk M, Valdés JJ, Cabezas-Cruz A, Vilcinskasa A. 2021. Potent activity of hybrid arthropod peptides linked by glycine spacers. International Journal of Molecular Sciences. 2021, 22(16), 8919.


Rügen N, Jenkins TP, Wielsch N, Vogel H, Hempel B-F, Süssmuth RD, Ainsworth S, Cabezas-Cruz A, Vilcinskas A, Tonk M. 2021. Hexapod Assassins’ Potion: Venom Composition and Bioactivity from the Eurasian Assassin Bug Rhynocoris iracundus. Biomedicines. Biomedicines, 9(7), 819.

Pacheco I, Díaz-Sánchez S, Contreras M, Villar M, Cabezas-Cruz A, Gortázar C, de la Fuente J. Probiotic bacteria with high alpha-Gal content protect zebrafish against mycobacteriosis. Pharmaceutical. 14(7), 635.

Artigas-Jerónimo S, Villar M, Cabezas-Cruz A, Caignard G, Vitour D, Richardson J, Lacour S, Attoui H, Bell-Sakyi L, Allain E, Nijhof A, Militzer N, Socias SP, de la Fuente J. 2021. Tick Importin-α is implicated in the interactome and regulome of the cofactor Subolesin. Pathogens. 10(4), 457.

Meloa ALT, Luob T, Zhang X, Muraroa LS, Pereira NA, Cabezas-Cruz A, Dantas-Torres F, McBride JW, Moura de Aguiar DM. 2021. Serological evidence of Ehrlichia minasensis infection in Brazilian dogs. Acta Trop. 219:105931

Bamgbose T, Anvikar AR, Alberdi P, Abdullahi IO, Inabo HI, Bello M, Cabezas-Cruz A, de la Fuente J. Functional food for the stimulation of the immune system against malaria. Probiotics and Antimicrobial Proteins. DOI: 10.1007/s12602-021-09780-w

Mateos-Hernández L, Pipová N, Allain E, Henry C, Rouxel C, Lagrée A-C, Haddad N., Boulouis H-J, Valdés JJ, Alberdi P, de la Fuente J, Cabezas-Cruz A, Šimo L. 2021. Enlisting the Ixodes scapularis embryonic ISE6 cell line to investigate the neuronal basis of tick-pathogen interactions. Pathogens. 10(1):E70.

Pacheco I, Fernández de Mera IG, Brito FF, Torrijos EG, Villar M, Contreras M, Lima J, Doncel-Perez E, Cabezas-Cruz A, Gortazar C, de la Fuente J. 2021. Characterization of the anti-α-Gal antibody profile in association with tick bites, allergic reactions, blood group and Guillain-Barré syndrome. Ticks Tick Borne Dis. 12(3):101651.

Muraro LS, Souza AO, Leite TNS, Cândido SL, Melo ALT, Toma HS, Carvalho MB, Dutra V, Nakasato L, Cabezas-Cruz A, de Aguiar DM. 2021. First evidence of Ehrlichia minasensis infection in horses from Brazil. Pathogens. 10(3), 265.

de la Fuente J, Armas O, Sánchez-Rodríguez L, Gortázar C, Lukashev AN. 2021. COVID-BCG Collaborative Working Group. Citizen science initiative points at childhood BCG vaccination as a risk factor for COVID-19. Transbound Emerg Dis. DOI: 10.1111/tbed.14097.



Mateos-Hernández L, Obregon D, Maye J, Borneres J, Versille N, de la Fuente J, Estrada-Peña A, Hodžić A, Šimo L, Cabezas-Cruz A. 2020. Anti-tick microbiota vaccine impacts Ixodes ricinus performance during feeding. Vaccines. 8(4), 702.

Estrada-Peña A, Cabezas-Cruz A, Obregón D. 2020. Behind taxonomic variability: The functional redundancy in the tick microbiome. Microorganisms 8(11):1829.

Hodžić A, de la Fuente J, Cabezas-Cruz A. 2020. COVID-19 in the Developing World: Is the Immune Response to α-Gal an Overlooked Factor Mitigating the Severity of Infection? ACS Infectious Diseases. DOI: 10.1021/acsinfecdis.0c00747.

Hodžić A, Mateos-Hernández L, de la Fuente J, Cabezas-Cruz A. 2020. α-Gal-based vaccines: Advances, opportunities, and perspectives. Trends Parasitol. 36 (12): 992-1001.

Rego ROM, Lopez JE, Cabezas-Cruz A. 2020. Editorial: Biological Drivers of Vector-Pathogen Interactions. Front Cell Infect Microbiol. DOI: 10.3389/fcimb.2020.609495.

Obregón D, Corona B, Rodríguez-Mallon A, Gonzalez IR, Alfonso P, Ramos AN, Díaz-Sanchez AA, Navarrete MG, Fernández RR, Méndez L, Catanese HN, Peláez M, Gainza YA, Marrero-Perera R, Roblejo-Arias L, Lobo E, da Silva C, Fonseca AH, Roque E, Cabezas-Cruz A. 2020. Ticks and tick-borne diseases in Cuba, half a century of scientific research. Pathogens. 9(8), 616.

Mateos-Hernandez L, Risco-Castillo V, Torres-Maravilla E, Bermudez-Humaran L, Alberdi P, Hodžić A, Hernández-Jarguin A, Rakotobe S, Galon C, Devillers E, de la Fuente J, Guillot J, Cabezas-Cruz A. 2020. Gut microbiota abrogates anti-α-Gal IgA response in lungs and protects against experimental Aspergillus infection in poultry. Vaccines. 8(2), 285.

Hodžić A, Mateos-Hernández L, Fréalle E, Román-Carrasco P, Alberdi P, Pichavant M, Risco-Castillo V, Le Roux D, Vicogne J, Hemmer W, Auer H, Swoboda I, Duscher GG, de la Fuente J, Cabezas-Cruz A. 2020. Infection with Toxocara canis Inhibits the Production of IgE Antibodies to α-Gal in Humans: Towards a Conceptual Framework of the Hygiene Hypothesis? Vaccines. 8(2), 167.

Gobl J, Kumar DS, Sima R, Perner J, Kopáček P, Valdés JJ, Rego ROM, Cabezas-Cruz A. 2020. Histone methyltransferase DOT1L is involved in larval molting and second stage nymphal feeding in Ornithodoros moubata. Vaccines. 8(2), 157.

Obregón D, Corona-González B, Díaz-Sánchez AA, Roque E, Armas Y, Oliveira MCS, Cabezas-Cruz A. 2020. Efficient transovarial transmission of Babesia spp. in Rhipicephalus microplus ticks fed in water buffalo (Bubalus bubalis). Pathogens. 9(4), 280.

Doncel-Pérez E, Contreras M, Gómez-Hernando C, Vargas-Baquero E, Blanco-García J, Rodríguez-Gómez J, Velayos-Galán A, Cabezas-Cruz A, Gortázar C, de la Fuente J. 2020. What is the impact of the antibody response to glycan alpha-Gal in Guillain-Barré syndrome associated with SARS-CoV-2 infection?. Merit Research Journal of Medicine and Medical Sciences. 8(11), 730-737.

de la Fuente J, Gortázar C, Cabezas-Cruz A. 2020. Immunity to glycan α-Gal and possibilities for the control of COVID-19. Immunotherapy. Accepted!

Ghafar A, Abbas T, Rehman A, Sandhu ZuD, Cabezas-Cruz A, Jabbar A. 2020. Systematic Review of Ticks and Tick-Borne Pathogens of Small Ruminants in Pakistan. Pathogens. 9(11), 937.

Mohamed M, Obregón D, Chevillot A, Polack B, Julien C, Pollet T, Cabezas-Cruz A and Adjou K. 2020. Cryptosporidium parvum infection depletes butyrate producer bacteria in goat kid microbiome. Front. Microbiol. 11:548737.

Urra JM,  Ferreras-Colino E, Contreras M, Cabrera CM, Fernández  de  Mera IG,  Villar M, Cabezas-Cruz A, Gortázar C, de la Fuente J. 2020. The  antibody  response  to  the  glycan  α-Gal  correlates  with  COVID-19  disease symptoms. J Med Virol.. DOI: 10.1002/jmv.26575.

Ghafar A, Khan A, Cabezas-Cruz A, Gauci CG, Niaz S, Ayaz S, Mateos-Hernández L, Galon C, Nasreen N, Moutailler S, Gasser RB, Jabbar A. An assessment of the molecular diversity of ticks and tick-borne microorganisms of small ruminants in Pakistan. Microorganisms. 8(9), 1428.

de la Fuente J, Cabezas-Cruz A, Pacheco I. 2020. Alpha-Gal Syndrome: challenges to understanding sensitization and clinical reactions to alpha-gal. Expert Rev Mol Diagn. 20(9):905-911.

Mateos-Hernández L, Rakotobe S, Defaye B, Cabezas-Cruz A, Simo L. 2020. A capsule-based model for immature hard tick stages infestation on laboratory mice. J Vis Exp. (161). DOI: 10.3791/61430.

de la Fuente J, Gortázar C, Cabezas-Cruz A, Contreras M, Villar M, Pacheco I, Arias A, Mas A. 2020. Boosting anti-alpha-Gal immune response to control COVID-19. Royal Society Open Science Stage1 Registered Report, date of in-principle acceptance: 15/4/2020.

Pacheco I, Contreras M, Villar M, Risalde MA, Alberdi P, Cabezas-Cruz A, Gortázar C, de la Fuente J. 2020. Vaccination with a-Gal protects against mycobacterial infection in the zebrafish model of tuberculosis. Vaccines. 8(2), 195.

Estrada-Peña A, Cabezas-Cruz A, Obregón D. 2020. Resistance of tick gut microbiome to anti-tick vaccines, pathogen infection and antimicrobial peptides. Pathogens. 9(4), 309.

Villar M, Pacheco I, Merino O, Contreras M, Mateos-Hernández L, Prado E, Barros-Picanco DK, Lima-Barbero JF, Alberdi P, Fernández de Mera IG, Estrada-Peña A, Cabezas-Cruz A, de la Fuente J. 2020. Tick and host derived compounds modulate the biochemical properties of the cement complex substance. Vaccines.10(4), 555.

Contreras M, Pacheco I, Alberdi P, Díaz-Sánchez S, Artigas-Jerónimo S, Mateos-Hernández L, Villar M, Cabezas-Cruz A, de la Fuente J. 2020. Allergic reactions and immunity in response to tick salivary biogenic substances and red meat consumption in the zebrafish model. Front Cell Infect Microbiol. 10: 78.

Artigas-Jerónimo S, Comín JJP, Villar M, Contreras M, Alberdi P, Viera IL, Soto L, Cordero R, Valdés JJ, Cabezas-Cruz A, Estrada-Peña A, de la Fuente J. 2020. A Novel Combined Scientific and Artistic Approach for the Advanced Characterization of Interactomes: The Akirin/Subolesin Model. Vaccines 8(1), 77.

Ghafar A, Cabezas-Cruz A, Galon C, Obregon D, Gasser RB, Moutailler S, Jabbar A. 2020. Bovine ticks harbour a diverse array of microorganisms in Pakistan. Parasit Vectors. 13(1):1.​​

Díaz-Sánchez AA, Meli ML, Obregón DA, Fonseca-Rodríguez O, Cabezas-Cruz A, Hofmann-Lehmann R, Corona-González B. 2020. Development and application of a multiplex TaqMan RT-qPCR assay for the simultaneous detection of Anaplasma marginale and Theileria annulata and molecular characterization of Anaplasma marginale from cattle in Western Cuba. Ticks Tick Borne Dis. 11 (2), 101356.

Guarnizo TRM, Obregón D, Díaz-Sánchez AA, Cabezas-Cruz A, Gutiérrez LZ, Marrero SM, Corona-González B. Epidemiology and Genetic Diversity of Anaplasma marginale in Zamora-Chinchipe, Ecuador. 2020. Ticks Tick Borne Dis. 11(3):101380.




​​Cabezas-Cruz A, Hodžić A, Román-Carrasco P, Mateos-Hernández L, Duscher GG, Sinha DK, Wolfgang H, Swoboda I, Estrada-Peña A, de la Fuente J. 2019. Environmental and Molecular Drivers of the α-Gal Syndrome. Frontiers Immunol. 10:1210.

Cabezas-Cruz A, Tonk M, Bleackley MR, Valdés JJ, Barrero RA, Hernández-Jarguín A, Moutailler S, Vilcinskas A, Richard-Forget F, Anderson MA, Rodriguez-Valle M. 2019. Antibacterial and antifungal activity of defensins from the Australian paralysis tick, Ixodes holocyclus. Ticks Tick Borne Dis. 10(6):101269.

Cabezas-Cruz A, Gallois M, Fontugne M, Allain E, Denoual M, Moutailler S, Devillers E, Zientara S, Memmi M, Chauvin A, Agoulon A, Vayssier-Taussat M, Chartier C. 2019. Epidemiology and genetic diversity of Anaplasma ovis in goats in Corsica, France. Parasit Vectors. 12(1):3.

Cabezas-Cruz A, Allain E, Ahmad AS, Saeed MA, Rashid I, Ashraf K, Yousfi L, Shehzad W, Indjein L, Rodriguez-Valle M, Estrada-Peña A, Obregon D, Jabbar A, Moutailler S. 2019. Low genetic diversity of Ehrlichia canis associated to high coinfection rates in Rhipicephalus sanguineus s.l. Parasit Vectors. 12(1):12.

Cabezas-Cruz A, Alberdi P, Espinosa P, de la Fuente J. 2019. Tick-pathogen interactions: the metabolic perspective. Trends Parasitol. 35(4):316-328.

Cabezas-Cruz A, Estrada-Peña A, de la Fuente J. 2019. The good, the bad and the tick. Front Cell Dev Biol. 7:79.

Cabezas-Cruz A, Zweygarth E, Aguiar D M. 2019. Ehrlichia minasensis, an old demon with a new name. Ticks Tick Borne Dis.10(4):828-829.

Alberdi P*, Cabezas-Cruz A*-1, Espinosa PJ*, Villar M, Artigas-Jerónimo S, de la Fuente J-1. 2019. The redox metabolic pathways function to limit Anaplasma phagocytophilum infection and multiplication while preserving fitness in tick vector cells. Sci Rep. 9:13236. *Joint first authors and '1' joint corresponding authors.

Aguiar DM, Araújo JJP, Nakazato L, Bard E, Aguilar-Bultet L, Vorimore F, Popov VL, Colodel EM, Cabezas-Cruz A. 2019. Isolation and characterization of a novel pathogenic strain of Ehrlichia minasensis. Microorganisms. 7(11), 528.

Hodžić A, Mateos-Hernández L, Leschnik M, Alberdi P, Rego ROM, Contreras M, Villar M, de la Fuente J, Cabezas-Cruz A*, Duscher GG*. 2019. Tick Bites Induce Anti-α-Gal antibodies in dogs. Vaccines. 7(3), 114. * Joint corresponding authors.

Obregón D, Bard E, Abrial D, Estrada-Peña A, Cabezas-Cruz A. 2019. Sex-specific linkages between taxonomic and functional profiles of tick gut microbiomes. Front Cell Infect Microbiol. 9:298.

Hodžić A, Mateos-Hernández L, de la Fuente J, Cabezas-Cruz A. 2019. Delayed hypersensitivity reaction to mammalian galactose-α-1,3-galactose (α-Gal) after repeated tick bites in a patient from France. Ticks Tick Borne Dis. 10(5):1057-1059.

de la Fuente J, Pacheco I, Villar M, Cabezas-Cruz A. 2019. The Alpha-Gal syndrome: new insights into the tick-host conflict and cooperation. Parasit Vectors. 12(1):154.

Aguiar D M, Araujo J P, Nakazato L, Bard E, Cabezas-Cruz A. 2019. Complete Genome Sequence of Ehrlichia minasensis Isolated From Cattle. Microbiol Resour Announc. 8(15): e00161-19.

Estrada-Peña A and Cabezas-Cruz A. 2019. Phyloproteomic and functional analyses do not support a split in the genus Borrelia (phylum Spirochaetes). BMC Evol Biol. 19(1):54.

de la Fuente J, Pacheco I, Contreras M, Mateos-Hernández L, Villar M, Cabezas-Cruz A. 2019. Guillain-Barré and Alpha-gal Syndromes: Saccharides-induced Immune Responses. Explor Res Hypothesis Med. DOI: 10.14218/ERHM.2019.00027.

Díaz-Sánchez S, Estrada-Peña A, Cabezas-Cruz A, de la Fuente J. 2019. Evolutionary insights into the tick hologenome. Trends Parasitol. 35(9):725-737.

Fernández A M, Chaligiannis I, Cabezas-Cruz A, Papa A, Sotiraki S, de la Fuente J, de Mera I G F. 2019. Molecular identification of spotted fever group Rickettsia in ticks collected from dogs and small ruminants in Greece. Exp Appl Acarol. 78(3):421-430

Artigas-Jerónimo S, Alberdi P, Villar M, Cabezas-Cruz A, Espinosa PJ, Mateos-Hernández L, de la Fuente J. 2019. Anaplasma phagocytophilum modifies tick cell microRNA expression and upregulates isc-mir-79 to facilitate infection by targeting the Roundabout protein 2 pathway. Sci Rep. 9(1):9073.


Obregón D, Cabezas-Cruz A, Armas Y, Silva JB, Fonseca AH, André MR, P Alfonso, Oliveira MCS, Machado RZ, Corona-González B. 2019. High co-infection rates of Babesia bovis, B. bigemina and Anaplasma marginale in water buffalo in Western Cuba. Parasitol Res. 118(3):955-967.

Ortega-Morales AI, Nava-Reyna E, Ávila-Rodríguez V, González-Álvarez VH, Castillo-Martínez A, Siller-Rodríguez QK, Cabezas-Cruz A, Dantas-Torres F, Almazán C. 2019. Detection of Rickettsia spp. in Rhipicephalus sanguineus (sensu lato) collected from free-roaming dogs in Coahuila state, northern Mexico. Parasit Vectors. 12(1):130.

Tonk M, Pierot C, Cabezas-Cruz A, Rahnamaeian M, Khalife J, Vilcinskas A. 2019. The Drosophila melanogaster antimicrobial peptides Mtk-1 and Mtk-2 are active against the malarial parasite Plasmodium falciparum. Parasitol Res. 118(6):1993-1998.

Artigas-Jerónimo S, Estrada-Peña A, Cabezas-Cruz A, Alberdi P, Villar M, de la Fuente J. 2019. Modeling modulation of the tick regulome in response to Anaplasma phagocytophilum for the identification of new control targets. Front Physiol. 10:462.

Lima-Barbero JF, Sánchez MS, Cabezas-Cruz A, Mateos-Hernández L, Contreras M, de Mera IGF, Villar M, de la Fuente J. 2019. Clinical gamasoidosis and antibody response in two patients infested with Ornithonyssus bursa (Acari: Gamasida: Macronyssidae). Exp Appl Acarol. 78(4):555-564.




Cabezas-Cruz A, Espinosa PJ, Alberdi P, Šimo L, Valdés JJ, Mateos-Hernández L, Contreras M, Rayo MV, de la Fuente J. 2018. Tick galactosyltransferases are involved in α-Gal synthesis and play a role during Anaplasma phagocytophilum infection and Ixodes scapularis tick vector development. Sci Rep. 8(1): 14224.

Cabezas-Cruz A, Vayssier-Taussat M and Greub G. 2018. Tick-borne pathogen detection: what’s new? Microb Infect. 20(7-8):441-444.


Estrada-Peña A, Álvarez-Jarreta J, Cabezas-Cruz A. 2018. Reservoir and vector evolutionary pressures shape the adaptation of Borrelia. Infect Genet Evol. 66:308-318.


Couto J, Tonk M, Ferrolho J, Antunes S, Vilcinskas A, de la Fuente J, Domingos A, Cabezas-Cruz A. 2018. Antiplasmodial activity of tick defensins in a mouse model of malaria. Ticks Tick Borne Dis. 9(4):844-849.


Estrada-Peña A, Cabezas-Cruz A. 2018. Towards the integrative analysis of tick microbiome. Ticks Tick Borne Dis. 10(1):34-35.

Estrada-Peña A, Cabezas-Cruz A, Pollet T, Vayssier-Taussat M, Cosson JF. High throughput sequencing and network analysis disentangle the microbial communities of ticks and hosts within and between ecosystems. Front Cell Infect Microbiol. 8:236.


Avila A, Cabezas-Cruz A, Gissot M. 2018. mRNA export in the apicomplexan parasite Toxoplasma gondii: emerging divergent components of a crucial pathway. Parasit Vectors. 11(1):62.


Obregón D, Corona BG, de la Fuente J, Cabezas-Cruz A, Gonçalves RL, Antonio Matos C, Armas YV, Hinojosa Y, Alfonso P, Oliveira MCS, Machado RZ. 2018. Molecular evidence of the reservoir competence of water buffalo (Bubalus bubalis) for Anaplasma marginale in Cuba. Vet Parasitol. 13: 180-187.


Fernández de Mera IG, Blanda V, Torina A, Dabaja MF, El Romeh A, Cabezas-Cruz A, de la Fuente. 2018. Identification and molecular characterization of spotted fever group rickettsiae in ticks collected from farm ruminants in Lebanon. Ticks Tick Borne Dis. 9(1):104-108.


Díaz-Sánchez AA, Pires MS, Estrada CY, Cañizares EV, del Castillo Domínguez SL, Cabezas-Cruz A, Rivero EL, da Fonseca AH, Massard CL, Corona-González B. 2018. First molecular evidence of Babesia caballi and Theileria equi infections in horses in Cuba. Parasitol Res. 117(10):3109-3118.


Estrada-Peña A, Villar M, Artigas-Jerónimo S, López V, Alberdi P, Cabezas-Cruz A, de la Fuente. 2018. Use of graph theory to characterize human and arthropod vector cell protein response to infection. Front Cell Infect Microbiol. 8:265.

Artigas-Jerónimo S, Villar M, Cabezas-Cruz A, Valdés JJ, Estrada-Peña A, Alberdi P, de la Fuente J. 2018. Functional evolution of Subolesin/Akirin. Front Physiol. 9:1612




Cabezas-Cruz A, Mateos-Hernández L, Chmelař J, Villar M, de la Fuente J. 2017. Salivary Prostaglandin E2: Role in Tick-Induced Allergy to Red Meat. Trends Parasitol. 33(7): 495-498.


Cabezas-Cruz A and de la Fuente J. 2017. Immunity to α-Gal: the opportunity for malaria and tuberculosis control. Front Immunol. 8:1733.


Cabezas-Cruz A and de la Fuente J. 2017. Is the blood type an overlooked risk factor in epidemiological studies of the α-Gal syndrome? Allergy. 72(12):2044-2047.


Cabezas-Cruz A, Mateos-Hernández L, Alberdi P, Villar M, Riveau G, Hermann E, Schacht AM, Khalife J, Correia-Neves M, Gortazar C, de la Fuente J. 2017. Effect of blood type on anti-α-Gal immunity and the incidence of infectious diseases. Exp Mol Med. 49(3): e301.


Cabezas-Cruz A and de la Fuente J. 2017. Immunity to α-Gal: toward a single-antigen pan-vaccine to control major infectious diseases. ACS Central Science. 3(11):1140-1142.

Cabezas-Cruz A, Alberdi P, Valdés JJ, Villar M, de la Fuente J. 2017. Anaplasma phagocytophilum infection subverts carbohydrate metabolic pathways in the tick vector, Ixodes scapularis. Front Cell Infect Microbiol. 7:23.


Cabezas-Cruz A, Alberdi P, Valdes JJ, Villar M, de la Fuente J. 2017. Remodeling of tick cytoskeleton in response to infection with Anaplasma phagocytophilum. Front Biosci. 22(11):1830-1844.


Cabezas-Cruz A, Estrada-Peña A, Rego RO, De la Fuente J. 2017. Tick-pathogen ensembles: do molecular interactions lead ecological innovation? Front Cell Infect Microbiol. 7:74.


Cabezas-Cruz A, Espinosa PJ, Obregón DA, Alberdi P, de la Fuente J. 2017. Ixodes scapularis tick cells control Anaplasma phagocytophilum infection by increasing the synthesis of phosphoenolpyruvate from tyrosine. Front Cell Infect Microbiol. 7:375.

Gondard M, Cabezas-Cruz A, Charles RA, Vayssier-Taussat M, Albina E, Moutailler S. 2017. Ticks and Tick-Borne Pathogens of the Caribbean: Current Understanding and Future Directions for More Comprehensive Surveillance. Front Cell Infect Microbiol. 7:490.


Estrada-Peña A, de la Fuente J, Cabezas-Cruz A. 2017. Functional redundancy and ecological innovation shape the communities of tick-transmitted pathogens. Front Cell Infect Microbiol. 7:234.


de la Fuente J, Contreras M, Estrada-Peña A, Cabezas-Cruz A. 2017. Targeting a global health problem: Vaccine design and challenges for the control of tick-borne diseases. Vaccine. 35(38): 5089-5094.


de la Fuente J, Antunes S, Bonnet S, Cabezas-Cruz A, Domingos AG, Estrada-Peña A, Johnson N, Kocan KM, Mansfield KL, Nijhof AM, Papa A, Rudenko N, Villar M, Alberdi P, Torina A, Ayllón N, Vancova M5, Golovchenko M, Grubhoffer L, Caracappa S, Fooks AR, Gortazar C, Rego ROM. 2017. Tick-pathogen interactions and vector competence: identification of molecular drivers for tick-borne diseases. Front Cell Infect Microbiol. 7:114.


Mateos-Hernández L, Villar M, Moral A, Rodríguez CG, Arias TA, de la Osa V, Brito FF, Fernández de Mera I G, Alberdi P, Ruiz-Fons F, Cabezas-Cruz A, Estrada-Peña A, de la Fuente J. 2017. Tick-host conflict: Immunoglobulin E antibodies to tick proteins in patients with anaphylaxis to tick bite. Oncotarget. 8(13):20630-20644.


Contreras M, Alberdi P, Mateos-Hernandez L, Fernández De Mera I G, Garcia-Perez A L, Vancova M, Villar M, Ayllón N, Cabezas-Cruz A, Valdés JJ, Stuen S, Gortazar C, de la Fuente J. 2017. Anaplasma phagocytophilum MSP4 and HSP70 Proteins Are Involved in Interactions with Host Cells during Pathogen Infection. Front Cell Infect Microbiol. 7:307.


Fernandez-de-Mera I G, Chaligianis I, Hernández-Jarguín A, Villar M, Mateos-Hernández L, Papa A, Sotiraki S, Ruiz-Fons F, Cabezas-Cruz A, Gortázar C, de la Fuente J. 2017. Combination of RT-PCR and proteomics for the identification of Crimean-Congo hemorrhagic fever virus in ticks. Heliyon. 3(2017): e00353.


González-Álvarez VH, Fernández de Mera IG, Cabezas-Cruz A, de la Fuente J, Ortega-Morales AI, Almazán C. 2017. Molecular survey of Rickettsial organisms in ectoparasites from a dog shelter in Northern Mexico. Vet Parasitol. 10: 143-148




Cabezas-Cruz A, Tonk M, Bouchut A, Pierrot C, Pierce RJ, Kotsyfakis M, Rahnamaeian M, Vilcinskas A, Khalife J, Valdés JJ. 2016. Antiplasmodial activity is an ancient and conserved feature of tick defensins. Frontiers Microbiol. 7:1682.


Cabezas-Cruz A, Estrada-Peña A, Valdés JJ, de la Fuente J. 2016. Be aware of ticks when strolling through the park. Front Young Minds. 4(24).


Cabezas-Cruz A, Valdés JJ, de la Fuente J. 2016. Control of vector-borne infectious diseases by human immunity against α-Gal. Expert Rev Vaccines. 15(8):953-955.


Cabezas-Cruz A, Alberdi P, Ayllón N, Valdés JJ, Pierce R, Villar M, de la Fuente J. 2016. Anaplasma phagocytophilum increases the levels of histone modifying enzymes to inhibit cell apoptosis and facilitate pathogen infection in the tick vector, Ixodes scapularis. Epigenetics. 11(4):303-19.

Figure selected for “Cover art” of Vol. 11, 2016, Epigenetics.


Cabezas-Cruz A, Zweygarth E, Vancová M, Broniszewska M, Grubhoffer L, Passos LMF, Ribeiro MFB, Alberdi P, de la Fuente J. 2016. Ehrlichia minasensis sp. nov., isolated from the tick Rhipicephalus microplus. Int J Syst Evol Microbiol. 66:1426-1430.


Valdés J J*, Cabezas-Cruz A*, Sima R, Butterill PT, Růžek D, Nuttall PA. 2016. Substrate prediction of Ixodes ricinus salivary lipocalins differentially expressed during Borrelia afzelii infection. Sci Rep. 6:32372.

*Joint first authors.


Tellier G, Lenne A, Cailliau-Maggio K, Cabezas-Cruz A, Valdés JJ, Martoriati A, Aliouat el M, Gosset P, Delaire B, Fréville A, Pierrot C, Khalife J. 2016. Identification of Plasmodium falciparum translation initiation 1 eIF2β subunit: direct interaction with Protein Phosphatase type 1. Front Microbiol. 7:777.


de la Fuente J, Villar M, Cabezas-Cruz A, Estrada-Peña A, Ayllón N, Alberdi P. 2016. Tick-host-pathogen interactions: conflict and cooperation. PLoS Pathogens. 12(4): e1005488.


Estrada-Peña A, de la Fuente J, Cabezas-Cruz A. 2016. A comparison of the performance of regression models of Amblyomma americanum (L.) (Ixodidae) using life cycle or landscape data from administrative divisions. Ticks Tick Borne Dis. 7(4):624-30.


Ferrolho J, Antunes S, Santos AS, Velez R, Padre L, Cabezas-Cruz A, Santos-Silva MM, Domingos A. 2016. Detection and phylogenetic characterization of Theileria spp. and Anaplasma marginale in Rhipicephalus bursa in Portugal. Ticks Tick Borne Dis. 7(3): 443–448.


de la Fuente J, Villar M, Estrada-Peña A, Cabezas-Cruz A, Kocan KM. 2016. Anaplasma phagocytophilum uses similar strategies to establish infection in tick vectors and vertebrate hosts. Trends Microbiol. 24(3): 173–180.


Almazán C, González-Álvarez H, García-Fernández I, Cabezas-Cruz A, Rodríguez-Martínez R, de la Fuente J. 2016. Molecular identification and characterization of Anaplasma platys and Ehrlichia canis in dogs in Mexico. Ticks Tick Borne Dis. 7(2):276-283.


Noda AA, Rodríguez I, Miranda J, Mattar S, Cabezas-Cruz A. 2016. First Report of Spotted Fever Group Rickettsia in Cuba. Ticks Tick Borne Dis. 7 (2016): 1057–1058.


Alberdi P, Espinosa PJ, Cabezas-Cruz A, de la Fuente J. 2016. Anaplasma phagocytophilum manipulates host cell apoptosis by different mechanisms to establish infection. Vet Sci. 3(3): doi: 10.3390/vetsci3030015.


Villar M, López V, Ayllón N, Cabezas-Cruz A, López JA, Vázquez J, Alberdi P, de la Fuente J. 2016. The intracellular bacterium Anaplasma phagocytophilum selectively manipulates the levels of vertebrate host proteins in the tick vector Ixodes scapularis. Parasit Vectors. 9:467.


Estrada-Peña A, Sprong H, Cabezas-Cruz A, de la Fuente J, Ramo A, Coipan EC. 2016. Nested coevolutionary networks shape the ecological relationships of ticks, hosts and the Lyme disease bacteria, Borrelia burgdorferi. Parasit Vectors. 9:517.




Cabezas-Cruz A, Mateos-Hernández L, Pérez-Cruz M, Valdés JJ, Mera IGF, Villar M, de la Fuente J. 2015. Regulation of the immune response to α-gal and vector-borne diseases. Trends Parasitol. 31(10): 470-476.


Cabezas-Cruz A, Valdés JJ, Lancelot J, Pierce RJ. 2015. Fast evolutionary rates associated with functional loss in class I glucose transporters of Schistosoma mansoni. BMC Genomics. 16(1):980.


Cabezas-Cruz A and  de la Fuente J. 2015. Anaplasma marginale major surface protein 1a: a marker of strain diversity with implications for control of bovine anaplasmosis. Ticks Tick Borne Dis. 6(2015):205-210.


Cabezas-Cruz A, Zweygarth E, Broniszweska M, Passos LM, Ribeiro MF, Manrique M, Tobes R, de la Fuente J. 2015. Complete Genome Sequence of Ehrlichia mineirensis, a Novel Organism Closely Related to Ehrlichia canis with a New Host Association. Genome Announc. 3(1):e01450-14.

Avila LA, Aps LR, Sukthankar P, Ploscariu N, Guldur S, Šimo L, Szoszkiewicz R, Park Y, Lee SY, Iwamoto T, Tomich JM. 2015. Branched amphiphilic cationic oligo-peptides form peptiplexes wih DNA: A study of their biophysical properties and transfection efficiency. Mol Pharm. 12 (3), pp 706–715

Tonk M*, Cabezas-Cruz A*, Valdés JJ, Rego RO, Grubhoffer L, Estrada-Peña A, Vilcinskas A, Kotsyfakis M, Rahnamaeian M. 2015. Ixodes ricinus defensins attack distantly-related pathogens. Dev Comp Immunol. 53(2):358-365.

*Joint first authors.


Lancelot J, Cabezas-Cruz A, Caby S, Marek M, Schultz J, Romier C, Sippl W, Jung M, Pierce RJ. 2015. Schistosome sirtuins as drug targets. Future Med Chem. 7(6): 765-782.


Alberdi P, Ayllón N, Cabezas-Cruz A, Bell-Sakyi L, Zweygarth E, Stuen S, de la Fuente J. 2015. Infection of Ixodes spp. tick cells with different Anaplasma phagocytophilum isolates induces the inhibition of apoptotic cell death. Ticks Tick Borne Dis. 6(6):758-767.


Tonk M, Knorr E, Cabezas-Cruz A, Valdés JJ, Kollewe C, Vilcinskas A. 2015. Tribolium castaneum defensins are primarily active against Gram-positive bacteria. J Invertebr Pathol. 132: 208-215.


Kocan KM, de la Fuente J, Cabezas-Cruz A. 2015. The genus Anaplasma: New challenges after reorganization. Rev Sci Tech. 34(2):577-586.


Estrada-Peña A, de la Fuente J, Ostfeld R, Cabezas-Cruz A. 2015. Interactions between tick and transmitted pathogens evolved to minimise competition through nested and coherent networks. Sci Rep. 5: 10361.


Ayllón N, Villar M, Galindo RC, Kocan KM, Šíma R, López J, Vázquez J, Alberdi P, Cabezas-Cruz A, Kopáček P, de la Fuente J. 2015. Systems Biology of Tissue-Specific Response to Anaplasma phagocytophilum Reveals Differentiated Apoptosis in the Tick Vector Ixodes scapularis. PLoS Genetics. 11(3): e1005120.


Lis K, Fernández de Mera IG, Popara M, Nieves A, Cabezas-Cruz A, Ayllón N, Zweygarth E, Passos LM, Broniszewska M, Villar M, Kocan KM, Ribeiro MF, Pfister K, de la Fuente J. 2015. Molecular and immunological characterization of three strains of Anaplasma marginale grown in cultured tick cells. Ticks Tick Borne Dis. 6(2015):522-529.


de la Fuente J, Díez-Delgado I, Contreras M, Vicente J, Cabezas-Cruz A, Manrique M, Tobes R, López V, Romero B, Domínguez L, Garrido JM, Juste R, Gortazar C. 2015. Complete genome sequence of field isolates of Mycobacterium bovis and Mycobacterium caprae. Genome Announc. 3(3):e00247-15.


Baêta BA, Ribeiro Carla CDU, Teixeira RC, Cabezas-Cruz A, Passos LM, Zweygarth E, Fonseca AH. 2015. Characterization of two strains of Anaplasma marginale isolated from cattle in Rio de Janeiro, Brazil, after propagation in tick cell culture. Ticks Tick Borne Dis. 6(2):141-145.


Ayllón N, Naranjo V, Hajdušek O, Villar M, Galindo RC, Kocan KM, Alberdi P, Šíma R, Cabezas-Cruz A, Rückert C, Bell-Sakyi L, Kazimírová M, Havlíková S, Klempa B, Kopáček P, de la Fuente J. 2015. Nuclease Tudor-SN is involved in tick dsRNA-mediated RNA interference and feeding but not in defense against flaviviral or Anaplasma phagocytophilum rickettsial infection. PLoS ONE. 10(7):e0133038.


Villar M, Ayllon N, Kocan KM, Bonzon-Kulichenko E, Alberdi P, Blouin EF, Weisheit S, Mateos-Hernandez L, Cabezas-Cruz A, Bell-Sakyi L, Vancová M, Bílý T, Meyer DF, Sterba J, Contreras M, Rudenko N, Grubhoffer L, Vázquez J, de la Fuente J. 2015. Identification and characterization of Anaplasma phagocytophilum proteins involved in infection of the tick vector, Ixodes scapularis. PLoS ONE. 10(9):e0137237.


Pinheiro-Silva R, Borges L, Coelho LP, Cabezas-Cruz A, Valdés JJ, do Rosário V, de la Fuente J, Domingos A. 2015. Gene expression changes in the salivary glands of Anopheles coluzzii elicited by Plasmodium berghei infection. Parasit Vectors. 8:485.

de la Fuente J, Estrada-Peña A, Cabezas-Cruz A, Brey R. 2015. Flying ticks: Anciently evolved associations that constitute a risk of infectious disease spread. Parasit Vectors. 8:538.


de la Fuente J, Diez I, Contreras M, Vicente J, Cabezas-Cruz A, Tobes R, Manrique M, López V, Romero B, Bezos J, Dominguez L, Sevilla IA, Garrido JM, Juste R, Madico G, Jones-López E, Gortazar C. 2015. Comparative genomics of field isolates of Mycobacterium bovis and M. caprae provides evidence for possible correlates with bacterial viability and virulence. PLoS Negl Trop Dis. 9(11):e0004232.




Cabezas-Cruz A, Valdés J, de la Fuente J. 2014. Cancer research meets tick vectors for infectious diseases. Lancet Infect Dis. 14(10): 916-917.


Cabezas-Cruz A and Valdés J J. 2014. Are ticks venomous animals? Front Zool. 11: 47.

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Cabezas-Cruz A, Valdés JJ, de la Fuente J. 2014. The glycoprotein TRP36 of Ehrlichia sp. UFMG-EV and related cattle pathogen Ehrlichia sp. UFMT-BV evolved from a highly variable clade of E. canis under adaptive diversifying selection. Parasit Vectors. 7:584.


Cabezas-Cruz A, Lancelot J, Caby S, Oliveira G, Pierce RJ. 2014. Epigenetic control of gene function in schistosomes: a source of therapeutic targets? Front Genet. 5:317.


Schwarz A*, Cabezas-Cruz A*, Kopecký J, Valdés JJ. 2014. Understanding the evolutionary structural variability and target specificity of tick salivary peptides using next generation transcriptome data. BMC Evol Biol. 14:4.

*Joint first authors.

Zweygarth E, Cabezas-Cruz A, Josemans AI, Oosthuizen MC, Matjila PT, Lis K, Broniszewska M, Schöl H, Ferrolho J, Grubhoffer L, Passos LM. 2014. In vitro culture and structural differences in the major immunoreactive protein gp36 of geographically distant Ehrlichia canis isolates. Ticks Tick Borne Dis. 5(4): 423–431.


Mutshembele AM, Cabezas-Cruz A, Mtshali MS, Thekisoe OM, Galindo RC, de la Fuente J. 2014. Epidemiology and evolution of genetic variability of Anaplasma marginale in South Africa. Ticks Tick Borne Dis. 5(6): 624-631.


Tonk M, Cabezas-Cruz A, Valdés JJ, Rego RO, Rudenko N, Golovchenko M, Bell-Sakyi L, de la Fuente J, Grubhoffer L. 2014. Identification and partial characterisation of new members of the Ixodes ricinus defensin family. Gene. 540 (2): 146–152.


Silva J B, Cabezas-Cruz A, Fonseca AH, Barbosa JD, de la Fuente J. 2014. Infection of water buffalo in Rio de Janeiro Brazil with Anaplasma marginale strains also reported in cattle. Vet Parasitol. 205 (2014): 730–734.


Tonk M, Cabezas-Cruz A, Valdés JJ, Rego RO, Chrudimská T, Strnad M, Šíma R, Bell-Sakyi L, Franta Z, Vilcinskas A, Grubhoffer L, Rahnamaeian M. 2014. Defensins from the tick Ixodes scapularis are effective against phytopathogenic fungi and the human bacterial pathogen Listeria grayi. Parasit Vectors. 7: 554.


Silva JB, Fonseca AH, Barbosa JD, Cabezas-Cruz A, de la Fuente J. 2014. Low genetic diversity associated with low prevalence of Anaplasma marginale in water buffaloes in Marajó Island, Brazil. Ticks Tick Borne Dis. 5(6): 801-804.




Cabezas-Cruz A, Passos LM, Lis K, Kenneil R, Valdés JJ, Ferrolho J, Tonk M, Pohl AE, Grubhoffer L, Zweygarth E, Shkap V, Ribeiro MF, Estrada-Peña A, Kocan KM, de la Fuente J. 2013. Functional and Immunological Relevance of Anaplasma marginale Major Surface Protein 1a Sequence and Structural Analysis. PLoS ONE. 8(6): e65243.


Cabezas-Cruz A, Vancová M, Zweygarth E, Ribeiro MF, Grubhoffer L, Passos LM. 2013. Ultrastructure of Ehrlichia mineirensis, a new member of the Ehrlichia genus. Vet Microbiol. 167(3–4): 455–458.


Pohl AE, Cabezas-Cruz A, Ribeiro MF, Silveira JA, Silaghi C, Pfister K, Passos LM. 2013. Detection of genetic diversity of Anaplasma marginale isolates in Minas Gerais, Brazil. Rev Bras Parasitol Vet. 22(1):129–135.


Zweygarth E, Schöl H, Lis K, Cabezas-Cruz A, Thiel C, Silaghi C, Ribeiro MF, Passos LM. 2013. In vitro culture of a novel genotype of Ehrlichia sp. from Brazil. Transbound Emerg Dis. 60 (Suppl. 2) 86–92.


Preston SG, Majtán J, Kouremenou C, Rysnik O, Burger LF, Cabezas-Cruz A, Chiong Guzman M, Nunn MA, Paesen GC, Nuttall PA, Austyn JM. 2013. Novel immunomodulators from hard ticks selectively reprogramme human dendritic cell responses. PLoS Pathogens. 9(6): e1003450.




Cabezas-Cruz A, Zweygarth E, Ribeiro MF, da Silveira JA, de la Fuente J, Grubhoffer L, Valdés JJ, Passos LM. 2012. New species of Ehrlichia isolated from Rhipicephalus (Boophilus) microplus shows an ortholog of the E. canis major immunogenic glycoprotein gp36 with a new sequence of tandem repeats. Parasit Vectors. 5: 291.

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